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PROGRAMMA SCIENTIFICO:
Day 1
14.00 Participant Registration
14.30 Introduction and welcome
Moderators: F. Demichelis, M. Landriscina
Session 1: State-of-the-art of management of genitourinary cancers: from treatment selection to personalized medicine, immunotherapy and RLT in:
14.45 – Prostate cancer
N. Brighi
15.05 – Urothelial cancer
U. Falagario
15.25 – Kidney cancer
L. Formisano
15.45 Discussion
16.15 Lecture: Personalized Medicine: Recent progress in prostate cancer therapy
E. Castro
16.45 Discussion
17.00 – 18.30 Roundtable discussion: participants share their experience on molecular testing in the prostate cancer setting
All participant
18.30 Conclusions
Day 2
9.00 Lecture: Circulating tumour DNA: a new frontier of research in urological tumours from localized disease to metastatic disease
V. Conteduca
Session 1: An overview of molecular methods in translational research 9.30 Next Generation Sequencing: advances and limits
F. Orlando
10.00 Current and emerging applications of droplet digital PCR
D. Wetterskog
10.30 Discussion
10.50 Coffee break
Session 2: Multiple tissue and germ line biomarkers to predict outcome in urological cancers
11.20 Immunohistochemistry and other immunostaining methods as important tools in biomarkers detection
F. Sanguedolce
11.50 Urologist’s perspective on emerging biomarkers in localized and locally advanced urological tumours
U. Falagario
12.20 Discussion
12.40 Lunch
Practical training 1: ctDNA testing: from the lab to the clinical practice
14.00 DNA extraction, qualitative and quantitative DNA analysis
G. Bruno – M. Garofoli
14.30 Project management of sample workflow
C. Nardella
15.00 Discussion
Practical training 2: Back-to-back: report of molecular diagnostics vs research output
15.20-16.00 Clinical interpretation of NGS data and computational analysis
N. Brighi – F. Orlando
16.00 Discussion
Session 3: Lab Experience across Translation Research Units in Italy and Europe
16.15 – 17.00 The clinical and translational research activities at: – Prostate Translational Unit, University of Foggia, Italy
V. Conteduca
– Department of Cellular, Computational and Integrative Biology, CIBIO, University of Trento, Italy
C. Nardella
– University College London Cancer Institute, London, UK
D. Wetterskog
17.00 -17.30 Roundtable discussion: participants share their experience on the current preceptorship
All participant
17.30 Take home messages
18.00 – 19.00 Conclusions and Test ECM
Medico chirurgo: Genetica medica, Oncologia, Radioterapia, Chirurgia generale, Urologia, Anatomia patologica, Laboratorio di genetica medica, Patologia clinica (laboratorio di analisi), Radiodiagnostica
Biologo: Biologo
Studente: Studente
